It’s one of the questions we hear most often — and the honest answer is: it depends!
Certain molecules scatter light more strongly than others, so the exact lower concentration limit for a Raman Optical Activity (ROA) measurement depends on the molecule being studied.
🧪 At the lower limit, we measure at around 30 mg/mL — but we’ve also worked with molecules in the 200 mg/mL range.
Curious what concentration you would need to measure the ROA of your sample? Reach out to us at contact@enantios.com to schedule a call with our applications team!








