Enantios ordered three isomers of ascorbic acid. The L-isoascorbic sample (the more expensive one) did not seem to have the correct Raman signature, but this was not fully clear from Raman alone.
Ascorbic Acid — Diastereomer Identification
Case study: which diastereomer of ascorbic acid do I have?
Why use Enantios technology?
- Supplier claimed the correct isomer had been sent, but the claim needed validating
- Traditional methods such as ORD and CD do not discriminate, and require large sample volumes
- Raman and ROA combined allow for clearer discrimination
Results
- The supplier sample was not L-isoascorbic as claimed
- Follow-up with the supplier produced no response and no refund
- Approaches to other suppliers offering a structure guarantee led to them eventually admitting they did not have the correct structure
Why use Enantios technology?
Fast, easy check of supplier quality claims.
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