Antibody Drug Conjugates — Tubulis Study

An application example from a study with Tubulis on antibody drug conjugates (ADCs).

Structure of a Tubulis antibody drug conjugate showing the mAb (trastuzumab), linker and drug (exatecan)
Raman spectra of Tubutecan, marker, ADC, mAb and partial mAb-linker
Signatures of the mAb, linker and drug measured separately and within the ADC
Drug-to-antibody ratio (DAR) in solution, with method development possible

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